References

Aagaard, P., Suetta, C., Caserotti, P., Magnusson, S. P., & Kjaer, M. (2010). Role of the nervous system in sarcopenia and muscle atrophy with aging: Strength training as a countermeasure. Scandinavian Journal of Medicine & Science in Sports, 20(1), 49–64. https://doi.org/10.1111/j.1600-0838.2009.01084.x
Adams, J., Cheng, D., & Berbarie, R. F. (2013). High-intensity, occupation-specific training in a series of firefighters during phase II cardiac rehabilitation. Baylor University Medical Center Proceedings, 26(2), 106–108. https://doi.org/10.1080/08998280.2013.11928931
Alentorn-Geli, E., Samuelsson, K., Musahl, V., Green, C. L., Bhandari, M., & Karlsson, J. (2017). The association of recreational and competitive running with hip and knee osteoarthritis: A systematic review and meta-analysis. Journal of Orthopaedic and Sports Physical Therapy, 47(6), 373–390. https://doi.org/10.2519/jospt.2017.7137
Ansari, S. et al. (2021). The effect of head loading on cervical spine in manual laborers. Asian Spine Journal, 15(6), 838–845. https://doi.org/10.31616/asj.2019.0221
Armstrong, N., Ward, A. J., & Lomax, M. (2019). Wearing body armour and backpack loads increase the likelihood of expiratory flow limitation and respiratory muscle fatigue during marching. Ergonomics, 62(9), 1181–1192. https://doi.org/10.1080/00140139.2019.1629638
Barton, J., & Pretty, J. (2010). What is the best dose of nature and green exercise for improving mental health? A multi-study analysis. Environmental Science & Technology, 44(10), 3947–3955. https://doi.org/10.1021/es903183r
Bauer, I. (2003). Inca trail porters: The health of local tourism employees as a challenge for travel medicine. Journal of Travel Medicine, 10(2), 94–99. https://doi.org/10.2310/7060.2003.31654
Baur, D., Lassalle, C., & Kurti, S. P. (2025). Thoracic load carriage impairs the acute physiological response to hypoxia in healthy males. Physiological Reports, 13(1), e70197. https://doi.org/10.14814/phy2.70197
Bean, J. F., Herman, S., Kiely, D. K., Frey, I. C., Leveille, S. G., Fielding, R. A., & Frontera, W. R. (2004). Increased velocity exercise specific to task (InVEST) training: A pilot study exploring effects on leg power, balance, and mobility in community-dwelling older women. Journal of the American Geriatrics Society, 52(5), 799–804. https://doi.org/10.1111/j.1532-5415.2004.52222.x
Beavers, D. P., Walkup, M. P., Weaver, A. A., Houston, D. K., Shapses, S. A., Kritchevsky, S. B., & Nicklas, B. J. (2025). Weighted vest use during intentional weight loss in older adults with obesity. JAMA Network Open, 8(7), e2516772. https://doi.org/10.1001/jamanetworkopen.2025.16772
Calamai, I., Eser, P., Jaeger, S., Grolimund, L., et al. (2024). Exclusive nasal breathing reduces work of breathing and improves exercise tolerance in patients with heart failure. Frontiers in Physiology, 15, 1344405. https://doi.org/10.3389/fphys.2024.1344405
Castillo, E. R. et al. (2014). Effects of pole compliance and step frequency on the biomechanics and economy of pole carrying during human walking. Journal of Applied Physiology, 117(5), 507–517. https://doi.org/10.1152/japplphysiol.00119.2014
Chen, Y. et al. (2024). GPR37 and its neuroprotective mechanisms: Bridging osteocalcin signaling and brain function. Frontiers in Cell and Developmental Biology. https://doi.org/10.3389/fcell.2024.1510666
Chrusch, A., & Kavin, M. (2021). Survey of musculoskeletal injuries, prehike conditioning, and on-trail injury prevention strategies self-reported by long-distance hikers on the Appalachian Trail. Wilderness and Environmental Medicine, 32(3), 322–331. https://doi.org/10.1016/j.wem.2021.04.004
Dallam, G. M., McClaran, S. R., Cox, D. G., & Foust, C. P. (2018). Effect of nasal versus oral breathing on VO2max and physiological economy in recreational runners following an extended period of nasal breathing training. International Journal of Kinesiology and Sports Science, 6(2), 22–29. https://doi.org/10.7575/aiac.ijkss.v.6n.2p.22
DeHart, N. E. (1999). Relationship between the talk test and ventilatory threshold [Master's thesis]. University of Wisconsin–Milwaukee.
Del Vecchio, A., Casolo, A., Negro, F., Scorcelletti, M., Bazzucchi, I., Enoka, R., Felici, F., & Farina, D. (2019). The increase in muscle force after 4 weeks of strength training is mediated by adaptations in motor unit recruitment and rate coding. The Journal of Physiology, 597(7), 1873–1887. https://doi.org/10.1113/JP277250
Dempsey, J. A., Romer, L., Rodman, J., Miller, J., & Smith, C. (2006). Consequences of exercise-induced respiratory muscle work. Respiratory Physiology & Neurobiology, 151(2–3), 242–250. https://doi.org/10.1016/j.resp.2005.12.015
Dhahbi, W., Briki, W., & Heissel, A. (2025). Physical activity to counter age-related cognitive decline: Benefits of aerobic, resistance, and combined training—a narrative review. Sports Medicine – Open, 11(1). https://doi.org/10.1186/s40798-025-00857-2
Dominelli, P. B., Sheel, A. W., & Foster, G. E. (2011). Effect of carrying a weighted backpack on lung mechanics during treadmill walking in healthy men. European Journal of Applied Physiology, 112(6), 2001–2012. https://doi.org/10.1007/s00421-011-2177-8
Eser, P., Calamai, P., Kalberer, A., et al. (2024). Improved exercise ventilatory efficiency with nasal compared to oral breathing in cardiac patients. Frontiers in Physiology, 15, 1380562. https://doi.org/10.3389/fphys.2024.1380562
Faghy, M. A., & Brown, P. I. (2014). Thoracic load carriage-induced respiratory muscle fatigue. European Journal of Applied Physiology, 114(5), 1085–1093. https://doi.org/10.1007/s00421-014-2839-4
Gai, Y., Zhong, Q., Zhang, Y., & Shen, M. (2025). Effects of weighted walking on gait stability in older adults: A systematic review and meta-analysis. Physical Activity and Health, 9(1), 4–14. https://doi.org/10.31489/3081-0531/2025-1-2/4-14
Greendale, G. A., Salem, G. J., Young, J. T., Damesyn, M., Marion, M. S., Wang, M.-Y., & Reuben, D. B. (2000). A randomized trial of weighted vest use in ambulatory older adults: Strength, performance, and quality of life outcomes. Journal of the American Geriatrics Society, 48(3), 305–311. https://doi.org/10.1111/j.1532-5415.2000.tb02651.x
Hackney, A. C. (2008). Effects of endurance exercise on the reproductive system of men: The “exercise-hypogonadal male condition.” Journal of Endocrinological Investigation, 31(10), 932–938. https://doi.org/10.1007/BF03346444
Hackney, A. C., & Lane, A. R. (2018). Exercise and the regulation of endocrine hormones. Progress in Molecular Biology and Translational Science, 135, 293–311. https://doi.org/10.1007/s42000-018-0010-z
Hamonko, M. T., McIntosh, S., Schimelpfenig, T., et al. (2011). Injuries related to hiking with a pack during National Outdoor Leadership School courses: A risk factor analysis. Wilderness and Environmental Medicine, 22(1), 2–6. https://doi.org/10.1016/j.wem.2010.09.010
Huang, Y. et al. (2019). Load carrying with flexible bamboo poles: Optimization of a coupled oscillator system. Journal of Experimental Biology, 222(23), jeb203760. https://doi.org/10.1242/jeb.203760
Jones, C. J., Rikli, R. E., & Beam, W. C. (1999). A 30-s chair-stand test as a measure of lower body strength in community-residing older adults. Research Quarterly for Exercise and Sport, 70(2), 113–119. https://doi.org/10.1080/02701367.1999.10608028
Journal of Clinical and Diagnostic Research. (2025). Impacts of occupational head loading on cervical degeneration: A systematic review. Journal of Clinical and Diagnostic Research. https://doi.org/10.7860/jcdr/2025/80480.22593
Karsenty, G. (2023). Osteocalcin: A multifaceted bone-derived hormone. Annual Review of Nutrition. https://doi.org/10.1146/annurev-nutr-061121-091348
Katsanos, C. S. et al. (2025). The impact of walking on BDNF as a biomarker of neuroplasticity: A systematic review. Brain Sciences, 15(3), 254. https://doi.org/10.3390/brainsci15030254
Kwon, Y.-H., Kang, K. W., & Chang, J. S. (2023). The talk test as a useful tool to monitor aerobic exercise intensity in healthy population. Journal of Exercise Rehabilitation, 19(3), 163–169. https://doi.org/10.12965/jer.2346170.085
Lee, D., Pate, R. R., Lavie, C. J., Sui, X., Church, T. S., & Blair, S. N. (2014). Leisure-time running reduces all-cause and cardiovascular mortality risk. Journal of the American College of Cardiology, 64(5), 472–481. https://doi.org/10.1016/j.jacc.2014.04.058
Lee, G.-Y., Seo, H.-D., & Lee, J.-H. (2025). Ventilatory responses to progressive treadmill speeds in nasal, oral, and oronasal breathing conditions. Journal of Exercise Rehabilitation, 21(2), 112–119. https://doi.org/10.12965/jer.2550184.092
Lefferts, W. K., Heffernan, K. S., & Hultquist, E. M. (2015). Vascular and central hemodynamic changes following exercise-induced heat stress. Vascular Medicine, 20(3), 222–229. https://doi.org/10.1177/1358863x14566430
Lo, G. H., Driban, J. B., Kriska, A. M., McAlindon, T. E., Souza, R. B., Petersen, N. J., Luo, H., Storti, K. L., Caserotti, P., Eaton, C. B., Hochberg, M. C., Jackson, R. D., Kwoh, C. K., Nevitt, M. C., & Suarez-Almazor, M. E. (2017). Is there an association between a history of running and symptomatic knee osteoarthritis? A cross-sectional study from the Osteoarthritis Initiative. Arthritis Care & Research, 69(2), 183–191. https://doi.org/10.1002/acr.22939
Lo, G. H., Musa, S. M., Driban, J. B., Kriska, A. M., McAlindon, T. E., Souza, R. B., Petersen, N. J., Storti, K. L., Eaton, C. B., Hochberg, M. C., Jackson, R. D., Kwoh, C. K., Nevitt, M. C., & Suarez-Almazor, M. E. (2018). Running does not increase symptoms or structural progression in people with knee osteoarthritis: Data from the Osteoarthritis Initiative. Clinical Rheumatology, 37(9), 2497–2504. https://doi.org/10.1007/s10067-018-4121-3
Lundberg, J. O., Weitzberg, E., Rinder, J., Rudehill, A., Jansson, O., Wiklund, N. P., Lundberg, J. M., & Alving, K. (1997). Heavy physical exercise decreases nitric oxide levels in the nasal airways in humans. Acta Physiologica Scandinavica, 159(1), 51–57. https://doi.org/10.1046/j.1365-201X.1997.553344000.x
Mahmod, S. R., Zourdos, M. C., Arent, S. M., et al. (2022). Regulated monosyllabic talk test vs. Counting talk test: Utterance rates and exercise intensity. Journal of Sports Sciences, 40(8), 857–864. https://doi.org/10.1080/02640414.2021.2021776
Maloiy, G. M. O., Heglund, N. C., Prager, L. M., Cavagna, G. A., & Taylor, C. R. (1986). Energetic cost of carrying loads: Have African women discovered an economic way of transporting goods? Nature, 319, 668–669. https://doi.org/10.1038/319668a0
Malville, N. J., Byrnes, W. C., Lim, H. A., & Basnyat, R. (2001). Commercial porters of eastern Nepal: Health status, physical work capacity, and energy expenditure. American Journal of Human Biology, 13(1), 44–56. https://doi.org/10.1002/1520-6300(200101/02)13:1<44::aid-ajhb1006>3.0.co;2-d
Manini, T. M., & Clark, B. C. (2012). Dynapenia and aging: An update. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 67(1), 28–40. https://doi.org/10.1093/gerona/glr010
Mapelli, M., Botta, S., Salvioni, E., Vignati, C., Mattavelli, I., Apostolo, A., Bonomi, A., Pugliese, L., & Agostoni, P. (2025). BreathWISE: A crossover randomized controlled trial on the effect of nasal vs. Oronasal breathing on cardiopulmonary exercise test parameters in healthy subjects. PLOS ONE, 20(4), e0326661. https://doi.org/10.1371/journal.pone.0326661
Martel, G. F., Cano de Clas, J., & Henson, A. M. (2002). Effects of strength training on cardiovascular responses to weight loaded walking in cardiac rehabilitation participants (No. 5; Vol. 34, p. S248). Abstract. Medicine & Science in Sports & Exercise. https://doi.org/10.1097/00005768-200205001-01389
Martel, G. F., Graziosi, Y. D., & Evelyn, T. A. (2003). Heavy resistance strength training improves cardiovascular responses to weight loaded walking in cardiac rehabilitation participants (Vol. 35, p. S174). Abstract. Medicine & Science in Sports & Exercise. https://doi.org/10.1097/00005768-200305001-00960
Martin, K. et al. (2022). Cognitive performance of military men and women during prolonged load carriage. BMJ Military Health. https://doi.org/10.1136/bmjmilitary-2021-002000
May, B. et al. (2015). The effects of load carriage and physical fatigue on cognitive performance. PLOS ONE, 10(7), e0130817. https://doi.org/10.1371/journal.pone.0130817
Moriishi, T., & Komori, T. (2025). Osteocalcin and GPR158: Linking bone and brain function. Frontiers in Cell and Developmental Biology. https://doi.org/10.3389/fcell.2025.1564751
National Institute for Occupational Safety and Health. (2014). Lieutenant suffers sudden cardiac death during the “pack test”—arizona. NIOSH Fire Fighter Fatality Investigation and Prevention Program, Report 2014-12. https://doi.org/10.26616/nioshfffacef201412
Nilsson, J., & Thorstensson, A. (1989). Ground reaction forces at different speeds of human walking and running. Acta Physiologica Scandinavica, 136(2), 217–227. https://doi.org/10.1111/j.1748-1716.1989.tb08655.x
O’Donnell, D. E., Hong, H. H., & Webb, K. A. (2000). Respiratory sensation during chest wall restriction and dead space loading in exercising men. Journal of Applied Physiology, 88(5), 1859–1869. https://doi.org/10.1152/jappl.2000.88.5.1859
Orr, R. M., Coyle, J., & Johnston, V. (2016). Self-reported load carriage injuries of military soldiers. International Journal of Injury Control and Safety Promotion, 24(2), 189–197. https://doi.org/10.1080/17457300.2015.1132731
Orr, R. M., Johnston, V., Coyle, J., & Pope, R. (2014). Reported load carriage injuries of the Australian Army soldier. Journal of Occupational Rehabilitation, 25(2), 316–322. https://doi.org/10.1007/s10926-014-9540-7
Orr, R. M., Pope, R., Johnston, V., & Coyle, J. (2014). Soldier occupational load carriage: A narrative review of associated injuries. International Journal of Injury Control and Safety Promotion, 21(4), 388–396. https://doi.org/10.1080/17457300.2013.833944
Prado-Novoa, O., Rodriguez, J., & Zorrilla-Revilla, G. (2022). Evaluating the human capacity of carrying loads without costs: A scoping review of the free-ride phenomenon. American Journal of Human Biology, 34(10), e23794. https://doi.org/10.1002/ajhb.23794
Rappelt, L., Held, S., Wiedenmann, T., & Donath, L. (2023). Effects of nasal- versus oral-only breathing on affect, physiology and exercise performance during 60 min of cycling. Frontiers in Physiology, 14, 1127946. https://doi.org/10.3389/fphys.2023.1127946
Reid, K. F., & Fielding, R. A. (2012). Skeletal muscle power: A critical determinant of physical functioning in older adults. Exercise and Sport Sciences Reviews, 40(1), 4–12. https://doi.org/10.1097/JES.0b013e31823b5f13
Ribeiro, F., Oliveira, N. L., & Pires, J. (2014). Treadmill walking with load carriage increases aortic pressure wave reflection. Revista Portuguesa de Cardiologia (English Edition), 33(7–8), 425–430. https://doi.org/10.1016/j.repce.2013.11.011
Roberts, M., Talbot, C., & Kay, A. D. (2018). Changes in postural sway and gait characteristics as a consequence of anterior load carriage. Gait & Posture, 66, 139–145. https://doi.org/10.1016/j.gaitpost.2018.08.039
Saeidifard, F., Medina-Inojosa, J. R., West, C. P., Olson, T. P., Somers, V. K., Bonikowske, A. R., Prokop, L. J., Vinciguerra, M., & Lopez-Jimenez, F. (2019). The association of resistance exercise with mortality: A systematic review and meta-analysis. European Journal of Preventive Cardiology, 26(15), 1647–1665. https://doi.org/10.1177/2047487319850718
Schram, V., & Hanson, P. (1988). Cardiovascular and metabolic responses to weight-loaded walking in cardiac rehabilitation patients. Journal of Cardiopulmonary Rehabilitation, 8(1), 28–32. https://doi.org/10.1097/00008483-198801000-00013
Shaw, J. M., & Snow, C. M. (1998). Weighted vest exercise improves indices of fall risk in older women. The Journals of Gerontology: Series A, 53A(1), M53–M58. https://doi.org/10.1093/gerona/53a.1.m53
Shei, R.-J., Chapman, R. F., Gruber, A. H., & Mickleborough, T. D. (2017). Respiratory effects of thoracic load carriage exercise and inspiratory muscle training as a countermeasure. Applied Physiology, Nutrition, and Metabolism, 42(5), 530–537. https://doi.org/10.1139/apnm-2016-0596
Skelton, D. A., Greig, C. A., Davies, J. M., & Young, A. (1994). Strength, power and related functional ability of healthy people aged 65–89 years. Age and Ageing, 23(5), 371–377. https://doi.org/10.1093/ageing/23.5.371
Sørensen, M., Larsen, B. J., & Petersen, J. (2020). Validity of the talk test as a method to estimate ventilatory threshold in cardiac patients. European Journal of Preventive Cardiology, 28(15), e22–e24. https://doi.org/10.1177/2047487320939549
Tang, Y. et al. (2024). Effects of aerobic exercise and resistance training on cognitive function: Comparative study based on FNDC5/irisin/BDNF pathway. Dementia and Geriatric Cognitive Disorders. https://doi.org/10.1159/000541093
Timmins, K. A., Leech, R. D., Batt, M. E., & Edwards, K. L. (2017). Running and knee osteoarthritis: A systematic review and meta-analysis. American Journal of Sports Medicine, 45(6), 1447–1457. https://doi.org/10.1177/0363546516657531
Tøien, T., Malmo, T., Espedal, L., & Wang, E. (2022). Maximal intended velocity enhances strength training-induced neuromuscular stimulation in older adults. European Journal of Applied Physiology, 122(12), 2627–2636. https://doi.org/10.1007/s00421-022-05045-8
Walsh, G. S., Low, D. C., & Arkesteijn, M. (2018). Effect of stable and unstable load carriage on walking gait variability, dynamic stability and muscle activity of older adults. Journal of Biomechanics, 73, 18–23. https://doi.org/10.1016/j.jbiomech.2018.03.018
Xu, Y., Yang, L., & Chen, K. (2019). Energetics of load carriage by bamboo carrying poles. ASME International Mechanical Engineering Congress and Exposition Proceedings. https://doi.org/10.1115/imece2019-10584
Zhang, X. et al. (2023). The role of IGF-1 in exercise to improve obesity-related cognitive dysfunction. Frontiers in Neuroscience, 17, 1229165. https://doi.org/10.3389/fnins.2023.1229165